Solitary rectal ulcer syndrome Clinicopathological Review of a Series of 19 Patients

نویسندگان

  • Katayoun Gohari Moghaddam Division of Pathology, Arya Hospital Tehran
  • Mohammad Vafaie Division of Coloproctology Iranian Clinic Tehran
  • Saeed erakhshani Division of Coloproctology Iranian Clinic Tehran
چکیده مقاله:

Background and Objectives: The etiology, pathophysiology, nomenclature and clinical manifes-tation of solitary rectal ulcer syndrome (SRUS) is poorly understood. Aim: To examine the pathology of mucosal changes and clinical features of this syndrome. Materials and Methods: The mucosal biopsies of 19 patients with clinical evidence of solitary rectal ulcer as been reviewed in accordance with their clinical complaints and endoscopic findings within three years. Results: SRUS has been seen in both sexes (11 male and 8 female) at the age ranging from 12 to 72 years (mean 29 years). The main clinical complaints were rectal bleeding, mucorrhea and perianal pain. The major rectoscopic findings were ulceration, erythema of mucosal surface, congestion and polypoid pattern. The significant pathologic features were mucosal architectural distortion, very superficial and irregular mucosal ulceration, fibrosis of lamina propria and thickening of the muscularis mucosa with splaying of its fibers and extension of muscularis fibers between the mucosal crypts. Conclusion: Although SRUS is rare but it can be confused clinically with other similar diseases such as inflammatory bowel disease,cloagenic carcinoma and other malignancies. It must be looked in differential diagnoses of pelvic disorders since it is well recognized on rectoscopic and morphologic basis.  

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

solitary rectal ulcer syndrome clinicopathological review of a series of 19 patients

background and objectives: the etiology, pathophysiology, nomenclature and clinical manifes-tation of solitary rectal ulcer syndrome (srus) is poorly understood. aim: to examine the pathology of mucosal changes and clinical features of this syndrome. materials and methods: the mucosal biopsies of 19 patients with clinical evidence of solitary rectal ulcer as been reviewed in accordance with the...

متن کامل

Solitary rectal ulcer syndrome: a case series.

A retrospective analysis of the clinical profile, endoscopic features and management of 22 children (age 18 months-18 years) diagnosed as solitary rectal ulcer syndrome is presented. The majority (81.8%) were ≥8 years of age. Rectal bleeding was the presenting feature in all the children. Mucorrhea, constipation, tenesmus and rectal prolapse were observed in 77.3%, 63.6%, 59% and 13.6% children...

متن کامل

Solitary rectal ulcer syndrome.

A 19 year female came with the complaints of rectal bleeding, constipation, griping abdominal pain and mucous discharge per rectum. Abdomen was tender on examination. Digital rectal examination in the squatting position revealed unterior rectal wall prolapse to the anal verge. Sigmoidoscopy and biopsy confirmed the diagnosis of Solitary Rectal Ulcer (S.R.U.) Syndrome.

متن کامل

A case of solitary rectal ulcer syndrome.

Solitary rectal ulcer syndrome(SRUS)은 1830년 Cruveilhier에 의해 처음 기술된 이후 1969년 Madigan과 Morson에 의 해 병리 소견이 연구되었다 1) . 젊은 성인에서 가장 빈도가 높으 며 2, 3) , 성별에 따른 빈도의 차이는 없거나, 일부 보고에서 여성 에 더 많은 것으로 알려져 있다 2, 4) . 아직 소아에 있어서 빈도에 관한 정확한 조사는 없으며, 다만 소아기에 매우 드문 질환으로 만 알려져 있고 소아의 SRUS에 대한 연구는 아직 소수에서 되 어있을 뿐이다 5-7) . 증상으로는 직장출혈, 점액성의 분비물, 긴 배 변시간, 뒤무직, 회음부의 국소적 통증을 주로 나타내며 5-10) , 일 반적으로 시행하는 검사에서 정상 소견을 보여 종종 오...

متن کامل

Solitary Rectal Ulcer Syndrome Mimicking Rectal Cancer

Solitary rectal ulcer syndrome (SRUS) is a rare benign and chronic rectal disease that has a wide spectrum of clinical presentations and variable endoscopic findings [1]. Rectal bleeding and abdominal pain are known as the main symptoms of SRUS. Usually, it is misdiagnosed through colonoscopy [2]; SRUS mimicking rectal cancer according to endoscopic findings, abdominopelvic computed tomography ...

متن کامل

Endoscopic ultrasonography of solitary rectal ulcer syndrome.

Solitary rectal ulcer syndrome (SRUS) is an uncommon poorly understood benign disorder of defecation. SRUS may simulate other disorders such as inflammatory bowel disease andneoplasms. Histopathological analysis forms the cornerstone of diagnosis for SRUS.Key histological features include fibromuscular obliteration of the lamina propria with splaying of the muscularis mucosae upward between the...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 1  شماره 2

صفحات  81- 86

تاریخ انتشار 2006-04-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023